This research investigates how mechanical forces regulate cell movement using a novel DNA-based force probe. By measuring the force required to halt actin growth, it provides new insights into the mechanics of cell migration. The findings could ultimately help develop strategies to prevent cancer metastasis by controlling tumour cell movement.

This research investigates how antiviral drug resistance develops by examining structural changes in viral proteins. Using protein crystallography, it identified why SARS-CoV-2 mutations prevent Paxlovid binding and discovered two compounds capable of inhibiting resistant viruses. The findings could guide development of more effective antivirals against future drug-resistant viral infections.

This research investigates how SUMO protein labeling regulates DNA repair after damage caused by sunlight and other stresses. Using yeast as a model organism, the study shows that SUMO helps recruit and remove repair proteins at damaged DNA sites. Understanding these signaling mechanisms may improve cancer prevention and treatment strategies.