This research explores biofiltration as a sustainable alternative to chemical water treatment. By supplying bacteria with nutrients like nitrogen and phosphorus, it improves removal of harmful organic matter. Results show a 20% efficiency increase, reducing chemical use and risks, and offering a cost-effective solution for safe drinking water worldwide.

This research explores brain stimulation as a safe, low-cost alternative to medication for children with neurological and mental health conditions. Despite promising results across disorders, only a small fraction of studies involve children. The work aims to expand evidence and access, improving global treatment options, especially for low-income populations.

This research addresses the lack of psychological support for bereaved parents in low-resource settings. After reviewing global evidence and consulting experts and parents, it aims to develop a culturally appropriate, community-based intervention in Malawi. The goal is scalable, evidence-based support integrated into health systems to reduce mental health risks after pregnancy and neonatal loss.

This research develops small-molecule treatments for chikungunya virus using a lock-and-key approach targeting viral proteins. A key challenge—molecular orientation (enantiomers)—was addressed with a new synthesis method producing over 95% effective molecules. The optimized compound, BDGR-651, shows promise as a future antiviral treatment for this debilitating disease.

Malaria still kills hundreds of thousands annually, while drug and insecticide resistance spread. This research shows that limiting mosquito sugar supply alters their evolution, reducing malaria parasite burden over generations. Targeting mosquito sugar metabolism offers a novel, sustainable strategy for controlling malaria and other mosquito-borne diseases.

This research explores a novel malaria control strategy by manipulating mosquito sugar metabolism. By forcing Anopheles stephensi to adapt to low-sugar diets across generations, mosquitoes evolved reduced malaria parasite loads. Targeting mosquito nutrition offers a promising alternative to insecticides for controlling malaria and other mosquito-borne diseases.

This research investigates how bacteria develop resistance to antibiotics, a growing global health threat. By identifying resistant bacteria and analysing how they chemically modify antibiotics, the work aims to uncover resistance mechanisms. These insights are essential for preserving antibiotic effectiveness and safeguarding treatments against life-threatening infections.

This research investigates how MRSA loses its antibiotic resistance by shedding the SCCmec genetic element. Environmental stressors such as heat and dryness increase this vulnerability, while antibiotics alone reinforce resistance. Understanding these mechanisms could enable new strategies to reverse resistance and improve treatment options for life-threatening MRSA infections.