This research investigates whether the diabetes drug dapagliflozin (DAPA) can be repurposed to treat metabolic dysfunction-associated steatotic liver disease (MASLD). Using laboratory models, it examines fat accumulation and NHE1 ion channel function, aiming to develop a cost-effective treatment for two closely linked metabolic diseases with one existing medicine.

This research investigates how misfolded Islet Amyloid Polypeptide (IAPP), a protein associated with Type 2 diabetes, affects blood clot formation. Laboratory experiments showed that misfolded IAPP creates unusually dense and resilient clots. These findings may help explain elevated cardiovascular risk in diabetes and identify new targets for preventing heart attacks and strokes.

This research investigates how Type 1 diabetes affects bone development during childhood and adolescence. Using high-resolution bone imaging and blood glucose data, the study explores whether blood sugar levels, variability, and disease duration influence bone health. Early findings suggest that diagnosis closer to puberty may be associated with lower bone density.