This research investigates how aging changes blood stem cells, causing them to produce excess sticky platelets that increase the risk of heart attack and stroke. By identifying the genetic mechanisms behind this age-related shortcut, the work aims to develop therapies that reduce cardiovascular disease while improving healing in patients with low platelet counts.

This research investigates how misfolded Islet Amyloid Polypeptide (IAPP), a protein associated with Type 2 diabetes, affects blood clot formation. Laboratory experiments showed that misfolded IAPP creates unusually dense and resilient clots. These findings may help explain elevated cardiovascular risk in diabetes and identify new targets for preventing heart attacks and strokes.