This research investigates how the protein Speedy influences breast tissue remodelling after pregnancy and its potential role in postpartum breast cancer. Mouse experiments suggest elevated Speedy reduces cell death but increases precancerous growths following carcinogen exposure. Understanding this mechanism could reveal new biomarkers and targets for earlier cancer detection.

Niall Ashfield investigates how cancer cells develop resistance to treatment. By recreating drug resistance in laboratory-grown cancer cells, his research examines the cellular changes that allow tumours to survive therapy. Identifying vulnerabilities in resistant cells could reveal alternative treatments, improve patient outcomes and support collaborations with pharmaceutical companies worldwide.