This research investigates how the protein Speedy influences breast tissue remodelling after pregnancy and its potential role in postpartum breast cancer. Mouse experiments suggest elevated Speedy reduces cell death but increases precancerous growths following carcinogen exposure. Understanding this mechanism could reveal new biomarkers and targets for earlier cancer detection.

Aideen McCabe investigates earlier ovarian cancer detection through improved laboratory cell models and RNA-based biomarkers. Her research aims to identify suitable cell lines, discover potential diagnostic indicators and inform future treatments. Guided by patient partners, the project seeks to translate laboratory discoveries into clinical advances that improve patient outcomes.