This research investigates macrophages, immune cells that regulate infection, tissue repair, and cancer responses. Through laboratory experiments and machine-learning models, it aims to predict macrophage function across different diseases and patients. The work could improve prognosis, guide treatments, evaluate drug safety, and forecast recovery following major illnesses and injuries.

This research investigates whether activation of the sympathetic nervous system can enhance tissue regeneration. Using engineered neural switches in mice, the study demonstrated improved healing after ear injury, including growth of nerves, blood vessels, and cartilage. The findings suggest that nervous system regulation may play an important role in future regenerative medicine therapies.

This research investigates whether regeneration can be induced in animals that normally lack regenerative abilities. Using nutrient factors such as amino acids and insulin, regeneration was stimulated in mice, jellyfish, and fruit flies. The findings reveal that regeneration is a coordinated whole-body process involving energy allocation, organ remodeling, and conserved nutrient signaling pathways.