This research investigates whether activation of the sympathetic nervous system can enhance tissue regeneration. Using engineered neural switches in mice, the study demonstrated improved healing after ear injury, including growth of nerves, blood vessels, and cartilage. The findings suggest that nervous system regulation may play an important role in future regenerative medicine therapies.
This research investigates whether regeneration can be induced in animals that normally lack regenerative abilities. Using nutrient factors such as amino acids and insulin, regeneration was stimulated in mice, jellyfish, and fruit flies. The findings reveal that regeneration is a coordinated whole-body process involving energy allocation, organ remodeling, and conserved nutrient signaling pathways.
This research explores neural remodeling—the process by which neurons form new connections after spinal cord injury. Using mouse models, the work identifies genes involved in detour pathways and enhances them through gene therapy, strengthening recovery. The goal is to develop future treatments that improve functional outcomes for people with central nervous system injuries.