This research investigates salivary gland damage caused by radiation therapy, disease and ageing. Focusing on cellular regulation, she identifies XBP1 as a key “manager” maintaining gland structure, cell survival and saliva production. Understanding this mechanism could guide future therapies for patients living with painful, incurable salivary gland dysfunction.
2020
This research explores neural remodeling—the process by which neurons form new connections after spinal cord injury. Using mouse models, the work identifies genes involved in detour pathways and enhances them through gene therapy, strengthening recovery. The goal is to develop future treatments that improve functional outcomes for people with central nervous system injuries.