This research targets rare genetic diseases caused by frameshift mutations using antisense oligonucleotides as “genetic band-aids.” By masking faulty DNA segments, it restores functional protein production. Demonstrated in muscular dystrophy models, this approach offers a scalable strategy to treat multiple rare diseases, addressing a major gap where most conditions lack effective therapies.

Bacteria can cause major industrial failures through metal corrosion, but most bacteria are harmless or beneficial. This research engineers protective bacterial strains to prevent corrosion by sealing cracks, forming biofilms, and outcompeting harmful microbes—transforming bacteria into a sustainable defense for metal infrastructure like pipelines, bridges, and buildings.