This research aims to solve the major weakness of mRNA vaccines—the need for constant cold storage—by packaging them inside ultra-stable protein “boxes” called encapsulins. These naturally robust containers protect mRNA in extreme environments. A working prototype now exists, offering the potential for globally distributable, freezer-free vaccines that remain effective anywhere.

Presbyopia, the age-related loss of near vision, occurs when the eye’s crystalline lens stiffens. A known lens-softening drug, Bistatin, affects too many eye structures to be safe. This research creates a targeted antibody–drug conjugate that delivers Bistatin only to the lens, restoring flexibility and offering a potential non-surgical treatment.

Brain surgeons struggle to distinguish tumor from healthy tissue in real time, risking life-altering surgical mistakes. This research uses polarimetric imaging and machine-learning algorithms to reveal tumor borders instantly by analysing subtle differences in tissue structure. Faster, clearer, real-time imaging could revolutionise brain surgery and dramatically improve patient outcomes.

My research presents a self-administered microneedle patch made from hyaluronic acid that delivers vaccines quickly, painlessly, and effectively. Testing with a COVID-19 spike RBD antigen shows immune responses comparable to traditional injections. The patches are low-risk, easy to use, and can be stored at room temperature for a month—ideal for widespread vaccination.