This research explores whether altering bodily sensations can change emotional experiences. By manipulating perceived heartbeat, blinking, and muscle tension through wearable devices and virtual reality, it demonstrates that emotions can be reshaped without changing physiology, opening new possibilities for treating trauma, anxiety, eating disorders, and other mental health conditions

This research develops a novel PEG-free lipid nanoparticle for gene therapy. Unlike conventional nanoparticles, which trigger immune responses after repeated use, the new formulation remains stable without PEG and performs even better. The approach could enable safer repeat dosing, improve treatment effectiveness, and expand access to life-changing gene therapies.

This research develops patient-specific digital twins of the heart to improve radiofrequency ablation for cardiac arrhythmias. By simulating heat transfer, tissue damage, and electrical activity, these computational models could improve treatment accuracy, reduce repeat procedures, accelerate medical device development, and advance the future of personalised cardiovascular medicine.

This research investigates how mechanical forces regulate cell movement using a novel DNA-based force probe. By measuring the force required to halt actin growth, it provides new insights into the mechanics of cell migration. The findings could ultimately help develop strategies to prevent cancer metastasis by controlling tumour cell movement.

This research develops hybrid lipo-polymeric nanoparticles that overcome major limitations of current mRNA vaccine technology. The particles can be freeze-dried, rapidly loaded with mRNA, and simultaneously deliver therapeutic drugs. Their flexibility improves vaccine storage and distribution while enabling powerful combination therapies, including enhanced cancer treatments with improved survival in preclinical models.

This research investigates how bacterial biofilms alter the mechanical properties of infected skin to improve microneedle-based drug delivery. By measuring tissue stiffness, structural integrity, and puncture resistance, it provides the evidence needed to design microneedles that can effectively penetrate biofilms, deliver antibiotics directly, and improve treatment of chronic wound infections.

This research develops self-sterilising polymer coatings that become highly acidic when exposed to moisture, rapidly destroying harmful bacteria such as MRSA and E. coli. Designed for hospitals, classrooms, and other high-contact surfaces, these materials could reduce infections without harsh chemicals, helping prevent the spread of antibiotic-resistant bacteria.

This research develops an affordable, scalable platform for recording electrical activity from brain organoids. Using innovative basket-shaped sensors made from a low-cost conductive material, the system enables simultaneous recording from dozens of mini-brains, accelerating drug discovery and improving our understanding of brain diseases with more human-relevant laboratory models.

This research engineers DNA-modified exosomes to deliver drugs precisely to cancer cells while avoiding healthy tissue. By disguising natural cell-targeting signals and adding programmable DNA targeting molecules, the platform could reduce treatment side effects and provide a modular delivery system adaptable to many cancers and other diseases.

This research developed NanoX, a nanoscale fluorescent sensor that images oxytocin release from individual neurons in real time. By revealing patterns of brain chemistry associated with mental health disorders, the technology could enable earlier diagnosis, improve understanding of neurochemical signaling, and support both preventive and personalized mental healthcare.