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Case Western Reserve
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Displaying 1 - 9 of 18
2026
Aplastic anemia occurs when immune cells attack blood-forming stem cells. Current diagnostics rely on DNA and RNA signals, which may not reflect what immune cells truly detect. Using immunopeptidomics, this research analyzes peptide fragments…
2026
Diabetes occurs when pancreatic beta cells that produce insulin are destroyed. Researchers are developing lab-grown beta cells from patient cells, but these cells often remain immature. By activating a missing gene, this study increases beta cell…
2026
Osteoarthritis affects millions and currently has no permanent cure. This research grows cartilage in the laboratory using bioreactors and mechanical loading to mimic natural joint conditions. The goal is a sealed system that produces customized…
2026
This qualitative study interviewed 41 participants to examine how followers influence leadership effectiveness. Findings show follower behaviors shape leader outcomes, team dynamics, and organizational performance. Effective followers demonstrate…
2026
Viruses build protective shells by following simple local connection rules between proteins. Using graph theory and network-based mathematical analysis, this research studies how these local interactions produce complex viral shell structures.…
2026
Global plastic waste exceeds 343 million tons annually, and most plastics are not effectively recycled. This research applies biaxial roll milling—an ancient metallurgy process—to strengthen recycled and biodegradable plastics. The technique…
2026
Most hearing tests are conducted only in English, limiting accurate diagnosis for multilingual patients. This research uses AI to generate multilingual speech recognition materials, create realistic audio stimuli, and automatically score responses.…
2026
Protein mutations can cause cellular proteins to stall or degrade before reaching their functional location, disrupting brain activity. This research investigates whether such delivery failures contribute to autism. By using drugs that stabilize…
2026
Cell therapy has cured some blood cancers but remains ineffective for most solid tumors and is extremely expensive. Tumor environments exhaust immune cells by depriving them of energy. This research develops metabolic support strategies that enhance…