Using Molecular Mechanics to Restore Protein Delivery in Autism - Emma Scritchfield

Year
2026
Organisation
Case Western Reserve
Tags
autism genetics research
protein trafficking defects
molecular chaperone drugs
neuroscience protein mutations
autism molecular mechanisms
personalized medicine neuroscience
cellular protein transport
neurodevelopmental disorder research
protein folding diseases
pharmacological chaperones
precision medicine autism
molecular neuroscience therapy
Summary

Protein mutations can cause cellular proteins to stall or degrade before reaching their functional location, disrupting brain activity. This research investigates whether such delivery failures contribute to autism. By using drugs that stabilize damaged proteins, scientists may restore their function and enable personalized treatments based on underlying molecular causes.