Human T-cell Leukemia Virus (HTLV) is a highly neglected virus that causes leukemia and neurodegeneration, with no current treatment. The researcher has developed siRNA-based RNA drugs that suppress the virus by up to 90%, prevent reactivation, and can be delivered via a nasal spray. This breakthrough could become the first effective antiviral therapy for HTLV.

This research aims to solve the major weakness of mRNA vaccines—the need for constant cold storage—by packaging them inside ultra-stable protein “boxes” called encapsulins. These naturally robust containers protect mRNA in extreme environments. A working prototype now exists, offering the potential for globally distributable, freezer-free vaccines that remain effective anywhere.

This research investigates how Plasmodium falciparum invades human red blood cells. By focusing on the neglected role of red cell surface structures, it aims to uncover molecular interactions essential for invasion. Understanding these mechanisms may guide the development of new treatments for drug-resistant malaria, a disease killing a child every minute.