My thesis describes how laboratory experiments recreate nuclear reactions occurring on accreting neutron stars. By developing a novel particle detection system, I achieved the first simultaneous neutron–proton measurements, enabling more complex studies that illuminate extreme matter, stellar evolution, and the cosmic origins of elements fundamental to life.
This research targets chronic lymphocytic leukemia relapse by focusing on Bruton’s Tyrosine Kinase (BTK), a key cancer-driving protein that often mutates and becomes drug-resistant. Using “molecular glues,” the project aims to degrade BTK—even when mutated—offering a new therapeutic strategy that could overcome resistance and improve outcomes for (chronic lymphocytic leukemia) CLL and other BTK-dependent cancers.