This research investigates the protein SLX4, a key coordinator of DNA repair. Using complementary techniques, it identifies 221 interacting proteins, most previously unknown. Findings reveal a complex network involved in genome maintenance, offering new insights into cellular repair mechanisms and improving understanding of diseases such as cancer.

This research develops a protein-based detection technology capable of identifying subtle molecular changes months before disease symptoms appear. By adapting nanopore sequencing with a protein “detangler,” it enables early warning for conditions like leukemia, shifting medicine from reactive treatment to proactive disease prevention.

This research provides the first-ever map of the honeybee gut protein interactome to understand how the parasite Nosema disrupts bee health. By isolating gut protein interactions and identifying them via mass spectrometry and computational analysis, the project uncovers how infection alters essential networks, paving the way for targeted, safer treatments for honeybee disease.