This research develops 3D-printed hydroxyapatite scaffolds that actively stimulate bone regeneration. Unlike traditional bone grafts, these synthetic scaffolds recruit stem cells and encourage new bone formation. Animal studies show promising healing results, raising the possibility of personalised, patient-specific implants that improve recovery from severe bone injuries and defects.

 

This research develops a physics-based method for measuring lung elasticity from medical imaging to predict which emphysema patients will benefit from lung valve treatment. By creating detailed elasticity maps, the work aims to improve treatment selection, enhance patient outcomes, and provide new quantitative tools for assessing lung health.

This research develops a robotic system capable of reproducing real-world knee motions and ACL injury mechanisms in human cadaver knees. The platform enables realistic testing of injury-prevention technologies, improves understanding of ACL rupture biomechanics, and may help reduce injury risk, particularly among women who experience higher ACL injury rates.

This research applies fluid mechanics, numerical simulations, and machine learning to model the brain’s waste-clearance system during sleep. By investigating how fluid moves through brain tissue and how aging or injury affect this process, the work aims to identify strategies for preventing or slowing neurodegenerative diseases such as Alzheimer's.

This research develops soft, tissue-like implantable sensors capable of monitoring molecular signals inside the body in real time. By combining high-performance electronics with flexible, biocompatible materials, these devices could detect inflammation, stress, or organ damage before symptoms arise, enabling earlier diagnosis and more personalized healthcare.

This research develops nanobubble-enhanced ultrasound imaging as an accessible alternative to MRI for cancer diagnosis. Tiny gas-filled nanoparticles amplify ultrasound signals and improve image quality, particularly in prostate cancer. The technology could reduce diagnostic delays, lower costs, and provide high-quality medical imaging to more patients worldwide.

This research develops antibacterial nanostructured surfaces inspired by natural materials such as cicada wings. The engineered surfaces physically rupture bacteria using nanoscale needle-like structures, avoiding traditional antibiotics and reducing the likelihood of antibiotic resistance. The technology could improve infection control in medical devices, implants, and hospital environments.

This research develops “nanozymes,” nanoparticle-based catalysts that activate cancer drugs directly at tumor sites. Instead of carrying large amounts of chemotherapy drugs, nanozymes locally trigger inactive drugs into their active form only within cancer tissue. Early mouse studies show effective tumor destruction with significantly reduced side effects compared to conventional chemotherapy.

This research uses artificial intelligence to predict the progression of Alzheimer’s disease and cancer using medical imaging data. By analyzing brain scans, tumor scans, and treatment responses, AI models can forecast disease development and treatment outcomes, enabling earlier intervention, more personalized care, and improved quality of life for aging populations.

This research develops nanoscale “smart package” delivery systems for PROTAC cancer drugs. Antibody nanogel conjugates selectively target cancer cells, enter them, and release therapeutic molecules while minimizing exposure to healthy tissue. The approach improves delivery efficiency and aims to reduce the severe side effects that often limit cancer treatment.