This research investigates the neurological causes of sleep dysfunction in people with myotonic dystrophy, a common multisystem muscular dystrophy. Using mouse models and brain activity monitoring, the study examines how diseased brains lose the ability to compensate for stress, providing new insights into sleep quality, cognition, and disease progression.

This research investigates how Melatonin regulates sleep using zebrafish models. The work identifies the MT1 receptor as essential for melatonin-induced sleep and suggests melatonin may reduce responsiveness to visual stimuli during sleep, helping explain how the brain increases arousal thresholds and maintains nighttime sleep states.