Corneal scarring causes widespread vision loss and is poorly treated by transplantation alone. This research develops a bioengineered corneal glue that both seals and heals wounds by promoting cell infiltration and reducing fibrosis. The approach enables scar-free healing, lowers transplant rejection risk, and offers a regenerative alternative to sutures and conventional sealants.

Presbyopia, the age-related loss of near vision, occurs when the eye’s crystalline lens stiffens. A known lens-softening drug, Bistatin, affects too many eye structures to be safe. This research creates a targeted antibody–drug conjugate that delivers Bistatin only to the lens, restoring flexibility and offering a potential non-surgical treatment.