The Role of Genetics in Opioid Use Disorder Treatment Options - Alannah McEvoy

Year
2024
Organisation
McMaster University
Tags
Opioid Use Disorder
Methadone Treatment
Genetics And Addiction
Polygenic Risk Score
Personalized Medicine Addiction
Opioid Overdose Prevention
Buprenorphine Treatment
Substance Use Disorder Research
Pharmacogenetics
Harm Reduction Canada
Methadone Dose Variability
Addiction Genomics
Summary

This research explores whether genetics can help predict how individuals with opioid use disorder respond to methadone treatment. Because methadone dose varies widely across patients, polygenic risk scores may one day support more personalized care, reduce relapse and overdose risk, and guide alternative treatment choices such as buprenorphine.