This research links two major treatment challenges in childhood acute lymphoblastic leukemia through ferroptosis, a lipid oxidation process regulated by selenium. By targeting selenium uptake in the brain and after chemotherapy, the work identifies potential new therapeutic strategies to reduce cancer cell survival and improve long-term treatment outcomes.
This research investigates unstable lipid oxidation products called epoxides, tracking how different fatty acids form them across various fats and oils. By improving detection and understanding of these pathways, the project supports better quality control in pet food and other lipid-based industries, helping reduce waste, extend shelf life, and promote sustainable practices.