Tiny errors in electrode placement can determine success or failure of Parkinson’s surgery. This research develops high-resolution Polarization Sensitive Optical Tomography to map brain anatomy at micrometer scale—over 100 times finer than MRI. Automated scanning and 3D reconstruction create detailed connectivity maps, improving surgical precision and neuroscience understanding.

This research explores how the hippocampus and prefrontal cortex communicate to support memory for sequences of events. By understanding how these brain regions track past, present, and future, the work aims to shed light on cognitive impairments seen in disorders such as Alzheimer’s disease and depression.

Mental health disorders disrupt neural connections in the brain, yet most treatments only manage symptoms. This research explores psychedelic-inspired drugs that restore lost brain connections without hallucinogenic effects, using automated imaging tools to identify compounds that rebuild neural structure and offer lasting recovery.