How Superheroes Become Supervillains Leukemic Edition - Ariana Sabzevari

Year
2025
Tags
cancer research
leukemia
immunology
T cells
DNA methylation
epigenetics
drug development
blood cancer
molecular biology
targeted therapy
medical research
oncology
translational science
UVA
Summary

This research investigates Large Granular Lymphocyte Leukemia, where protective T cells become cancerous. The project explores how DNA methylation silences normal T-cell function and tests drugs that reverse this process. By removing harmful chemical modifications, the goal is to restore immune cells to their healthy, protective “superhero” role.