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University of North Carolina
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2025
IBD patients have weakened gut microbes, leaving them with chronic inflammation and limited treatment options. This research engineers probiotic yeast with anchors, drug-carrying “backpacks,” and reprogrammed DNA to deliver targeted therapeutics…
2025
This research investigates HMGN proteins, which organize the genome and help cells access the correct genes. By mapping their activity and removing them with CRISPR, the study shows that HMGNs act as DNA “librarians.” Their dysfunction leads to gene…
2025
This research develops a risk-based model to prioritize gallbladder surgery for women with gallstones in high-risk regions. Using ultrasound and clinical data from Chilean women, the model predicts gallbladder cancer risk, enabling life-saving…